AI Product Engineer · Production Agents · Complex Domains

I turn complex work into AI products experts rely on.

Chris Van Buren
CVBAMBIGUOUS → AMBITIOUS
01

Production AI at scale

Grew Aligrade's product to $300K in revenue with two top-10 pharmaceutical customers after it acquired Grantease's technology. Previously scaled Grantease to $100K ARR in three months, with adoption at 30+ universities—including Stanford, Harvard, UPenn, Duke, UCLA, Mount Sinai, and Scripps.

02

Agent systems, end to end

Built production agent systems end to end—Pydantic AI supervisor/subagent orchestration, hybrid retrieval and parallel LLM reranking, validated outputs, collaborative document editing, resilient model routing, and agent-driven end-to-end evals.

03

Discovery to delivery

Turned ambiguous expert workflows into production AI products—from direct user discovery and product definition through architecture, evals, full-stack delivery, and production reliability.

04

Technical leadership

As Lead AI Engineer at Aligrade, owned AI architecture, technical roadmap, hiring, sprints, and delivery while leading three engineers and a product manager—and personally building the core systems. Published first-author AI evaluation research with Springer, co-authored LLM benchmarking with Lenovo and AMD, and wrote a three-part enterprise AI engineering series.

I am from Philadelphia, PA. I studied at Duke University. I currently live in Denver, CO.

I like playing and designing strategy board games, running, and tennis. My most useless skill is Etch A Sketch.

Aligrade

Lead AI Engineer · Aug 2025–Jul 2026

Production AI agents for biostatistics study planning

I joined after Aligrade acquired Grantease's technology. I led the team building production AI agents, owning AI architecture, the technical roadmap, engineering and product hiring, customer discovery, and delivery. The product grew to $300K in revenue with two top-10 pharmaceutical customers.

Built

A Pydantic AI multi-agent system with supervisor/subagent orchestration and validated outputs for regulated workflows; an AI-native collaborative document editor for precise, reviewable edits; hybrid BM25 and semantic retrieval with parallel LLM reranking; and a CLI that made the production application fully operable by agents for deeply interactive end-to-end evals.

  • $300K revenue
  • 2 top-10 pharma customers
  • <2-second retrieval
  • <$0.03 per search

Grantease

Co-founder & CTO · Sep 2024–Aug 2025

Visit Grantease

AI grant writing platform for research labs

I bootstrapped and scaled Grantease to $100K ARR in three months. The platform produced 1,000+ NIH proposals for researchers at 30+ universities before its technology was acquired by Aligrade, where I joined as Lead AI Engineer.

Built

A Next.js collaborative editor with an AI writing agent, Supabase and WorkOS enterprise authentication, DOCX/PDF ingestion, resilient fallback and structured-output recovery across five LLM providers, and an academic citation engine with automated data cleaning and Crossref metadata enrichment.

  • $100K ARR in 3 months
  • 1,000+ NIH proposals
  • 30+ universities
  • 60% faster proposal prep

Lenovo

Staff Data Scientist · 2021–2024

Production AI for enterprise workflows

I built and shipped RAG, NLP, and transformer products for three Fortune 500 customers, including enterprise knowledge retrieval, executive competitive intelligence, automated feedback routing, and assistive writing for people with ALS.

Built

Customer-facing RAG systems, evaluation pipelines, data workflows, low-latency transformer inference, and production deployment for on-premises enterprise environments.

  • Deployed for 3 Fortune 500 customers
  • 10+ hours/week saved on competitive intelligence

Editor MCP Public repository · Demo-ready

A collaborative document workspace for people and their AI agents.

I built a TypeScript MCP server and Tiptap/Yjs editor where agents make atomic, reviewable document changes instead of pasting text into chat. People can inspect, navigate to, accept, reject, or rewrite every proposed edit.

View source and demo
  1. 01

    Versioned semantic tools with revision guards and atomic edit groups

  2. 02

    Live shared state through Tiptap, ProseMirror, Yjs, and Hocuspocus

  3. 03

    Authenticated Streamable HTTP with OAuth and fail-closed validation

Research & writing

First author · TPCTC 2024

Evaluation Considerations of Synthetic Natural Language Datasets for Question Answering Applications

Designed and ran an experimental pipeline that generated synthetic question-answer datasets with four open-source LLM configurations, fine-tuned the same base model on each, and tested which dataset signals predicted downstream QA performance.

Found that semantic similarity can indicate domain diversity and that short chain-of-thought answers may flag lower-quality training data.

Co-author · TPCTC 2023

Benchmarking Large Language Models: Opportunities and Challenges

Co-authored a Lenovo and AMD review of how to compare LLM systems across training and inference—not only on accuracy and throughput, but also cost, energy, bias, trust, and sustainability.

Published by Springer in Lecture Notes in Computer Science; the chapter has been cited in subsequent benchmarking work.

Lenovo Press · Three-part engineering series

Making LLMs Work for Enterprise

I co-authored a practical series for enterprise teams building domain-specific RAG systems, from model selection and evaluation through synthetic dataset creation, LoRA fine-tuning, hardware sizing, latency, and production tradeoffs. I also developed a containerized framework that customers could use to implement the approach.

  1. 1 · Model selection & evaluation
  2. 2 · RAG dataset creation
  3. 3 · LoRA fine-tuning

Model training experiments

Graduate AI coursework · 2024

Transformers under noisy sequence data

Designed a card-shuffle simulator and trained encoder-only PyTorch transformers to test how model depth and increasing randomness affect ace-sequence prediction. Deeper models learned subtle structure in low-noise sequences; performance degraded as shuffle complexity increased.

  • PyTorch
  • Transformers
  • Synthetic data
Read the experiment

Graduate AI coursework · 2024

Imitation learning in a real-time game

Collected gameplay trajectories and trained PyTorch policies with behavioral cloning and DAgger for two-agent control. The strongest independent-policy pair scored 18 goals across 32 evaluation games and held the same scoring rate against unseen agents.

  • PyTorch
  • Imitation learning
  • DAgger
Read the experiment