I turn complex expert workflows into reliable AI products.

Chris Van Buren
CVBAMBIGUOUS → AMBITIOUS
01

Owned the outcome

Founded and scaled Grantease to $100K ARR, then led AI engineering and product delivery at Aligrade, translating expert research workflows into production systems.

02

Embedded with experts

Biostatisticians, life-sciences research teams, NIH-funded researchers, and scientific grant writers.

03

Translated work into product

Turned those workflows into retrieval and reuse tools, content review, literature search, citations, and reviewable document editing.

04

Engineered for production

Built multi-agent orchestration, hybrid retrieval and reranking, structured validation, resilient model routing, editing APIs, and end-to-end evaluations.

Aligrade · Lead AI Engineer · 2025–2026

Production AI agents for biostatistics study planning

I joined after Aligrade acquired Grantease's technology and led customer discovery, solution design, and production delivery for an AI study-planning product. I owned architecture, roadmap, hiring, and engineering execution while leading the AI engineering and product team.

Discovery → product

Interviewed biostatisticians to map how experts searched prior studies and reused approved methods, definitions, and code. Translated expert research workflows into tools for evidence retrieval, content reuse, and review for adherence, clarity, and internal consistency.

Engineering

Architected a Pydantic AI supervisor/subagent system with structured validation and editing APIs; built hybrid BM25 and semantic retrieval with parallel LLM reranking for large document collections; and made the production app agent-operable through a CLI for end-to-end evaluations, failure reproduction, and faster debugging.

  • Production deployments with design partners
  • Led AI engineering and product team

Grantease · Co-founder & CTO · 2024–2025

Visit Grantease

AI grant writing platform for research labs

I co-founded, built, and operated an AI grant-writing SaaS from zero to $100K ARR within three months. Researchers at 30+ universities produced 1,000+ NIH proposals before the technology was acquired by Aligrade.

Discovery → product

Their feedback informed literature search and automated citations; users reported working on as many as 10 proposals at once versus three under their previous manual process.

Engineering

Built the Next.js platform end to end: AI writing agent, collaborative editor, Supabase data layer, WorkOS enterprise authentication, and DOCX/PDF ingestion. Engineered fallbacks, structured-output recovery, and model tiering across five providers, plus citation data parsing, cleaning, and Crossref enrichment.

  • $100K ARR within 3 months of launch
  • 1,000+ NIH proposals produced
  • Adopted at 30+ universities
  • 60% faster proposal preparation

Lenovo · Staff AI Engineer · 2021–2024

Enterprise AI solutions and production ML

I worked across customer-facing enterprise solution delivery and production ML for Lenovo's public PC support operations, helping win three Fortune 500 customers and handing completed systems to production engineering teams.

Discovery → product

Owned technical discovery with enterprise customers, turning their domain and infrastructure constraints into fine-tuned LLM/RAG software, evaluation plans, and hardware requirements for on-premises deployment.

Engineering

Developed an XGBoost model and SHAP explainability layer trained on tens of thousands of historical support cases, improving held-out three-class accuracy from 65% to 95%. The scheduled production workflow scored every survey-eligible open support case across North America and Europe. I also built webhook monitoring and maintained localized responses and branching logic for a public-facing support chatbot.

  • Helped win 3 Fortune 500 customers
  • Production ML deployed across North America + Europe

Public engineering artifact

Editor MCP Public repository · Demo-ready

A collaborative document workspace for people and their AI agents.

I built a TypeScript MCP server and Tiptap/Yjs editor where agents make atomic, reviewable document changes instead of pasting text into chat. People can inspect, navigate to, accept, reject, or rewrite every proposed edit.

View source and demo
  1. 01

    Versioned semantic tools with revision guards and atomic edit groups

  2. 02

    Live shared state through Tiptap, ProseMirror, Yjs, and Hocuspocus

  3. 03

    Authenticated Streamable HTTP with OAuth and fail-closed validation

More building

Proto-Town Hardware Incubator · 2024

Built the place where other founders could build.

I helped launch a hardware-focused startup ranch, secured its first startup tenants, and built the prototyping workshop.

Research & writing

First author · TPCTC 2024

Evaluation Considerations of Synthetic Natural Language Datasets for Question Answering Applications

Designed and ran an experimental pipeline that generated synthetic question-answer datasets with four open-source LLM configurations, fine-tuned the same base model on each, and tested which dataset signals predicted downstream QA performance.

Found that semantic similarity can indicate domain diversity and that short chain-of-thought answers may flag lower-quality training data.

Co-author · TPCTC 2023

Benchmarking Large Language Models: Opportunities and Challenges

Co-authored a Lenovo and AMD review of how to compare LLM systems across training and inference—not only on accuracy and throughput, but also cost, energy, bias, trust, and sustainability.

Published by Springer in Lecture Notes in Computer Science; the chapter has been cited in subsequent benchmarking work.

Lenovo Press · Three-part engineering series

Making LLMs Work for Enterprise

I co-authored a practical series for enterprise teams building domain-specific RAG systems, from model selection and evaluation through synthetic dataset creation, LoRA fine-tuning, hardware sizing, latency, and production tradeoffs. I also developed a containerized framework that customers could use to implement the approach.

  1. 1 · Model selection & evaluation
  2. 2 · RAG dataset creation
  3. 3 · LoRA fine-tuning

Model training experiments

Graduate AI coursework · 2024

Transformers under noisy sequence data

Designed a card-shuffle simulator and trained encoder-only PyTorch transformers to test how model depth and increasing randomness affect ace-sequence prediction. Deeper models learned subtle structure in low-noise sequences; performance degraded as shuffle complexity increased.

  • PyTorch
  • Transformers
  • Synthetic data
Read the experiment

Graduate AI coursework · 2024

Imitation learning in a real-time game

Collected gameplay trajectories and trained PyTorch policies with behavioral cloning and DAgger for two-agent control. The strongest independent-policy pair scored 18 goals across 32 evaluation games and held the same scoring rate against unseen agents.

  • PyTorch
  • Imitation learning
  • DAgger
Read the experiment

Education

University of Texas at Austin

M.S. in Artificial Intelligence · Part-time · 2024–Present

Duke University

B.S.E. in Electrical & Computer Engineering · Certificate in Decision Science · 2017–2021

Technical toolkit

Languages
Python, TypeScript, SQL
AI & ML
PyTorch, Hugging Face Transformers, Pydantic AI, MCP, Langfuse, scikit-learn, XGBoost
Web & APIs
FastAPI, Node.js, Next.js, React
Data & infrastructure
AWS, Docker, Redis, PostgreSQL, pgvector, Supabase

I am from Philadelphia, PA. I studied at Duke University. I currently live in Denver, CO.

I like playing and designing strategy board games, running, and tennis. My most useless skill is Etch A Sketch.

On the nightstand

What I'm reading

01

Genius Makers

The Mavericks Who Brought AI to Google, Facebook, and the World

Cade Metz

02

Skunk Works

A Personal Memoir of My Years at Lockheed

Ben R. Rich & Leo Janos

03

Impro

Improvisation and the Theatre

Keith Johnstone

04

Abundance

How We Build a Better Future

Ezra Klein & Derek Thompson

05

Blood, Sweat & Chrome

The Wild and True Story of Mad Max: Fury Road

Kyle Buchanan

06

Lonesome Dove

Larry McMurtry

07

Arctic Dreams

Imagination and Desire in a Northern Landscape

Barry Lopez

08

Zero to One

Notes on Startups, or How to Build the Future

Peter Thiel & Blake Masters

09

No Rules Rules

Netflix and the Culture of Reinvention

Reed Hastings & Erin Meyer

10

Shoe Dog

A Memoir by the Creator of Nike

Phil Knight

11

The Art Thief

A True Story of Love, Crime, and a Dangerous Obsession

Michael Finkel

12

Dune Messiah

Frank Herbert

13

The Verge

Reformation, Renaissance, and Forty Years That Shook the World

Patrick Wyman

14

Persian Fire

The First World Empire and the Battle for the West

Tom Holland

15

Undaunted Courage

Meriwether Lewis, Thomas Jefferson, and the Opening of the American West

Stephen E. Ambrose

16

The Count of Monte Cristo

Alexandre Dumas

17

Kidnapped

Robert Louis Stevenson

18

The Shadow War

Inside Russia's and China's Secret Operations to Defeat America

Jim Sciutto

19

Elon Musk

Walter Isaacson

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